New prostaglandins from the chemically defended soft coral Plexaura nina.
نویسندگان
چکیده
Three new prostaglandins were isolated as minor constituents of the organic extract from the Caribbean soft coral Plexaura nina. The structures of the new natural products were established by means of spectral data analysis, including 2D NMR experiments. The unpalatability of the lipid extract of the coral and the defensive role of the major prostaglandin metabolites were determined by laboratory and field fish-feeding assays.
منابع مشابه
The origin of 15R-prostaglandins in the Caribbean coral Plexaura homomalla: molecular cloning and expression of a novel cyclooxygenase.
The highest concentrations of prostaglandins in nature are found in the Caribbean gorgonian Plexaura homomalla. Depending on its geographical location, this coral contains prostaglandins with typical mammalian stereochemistry (15S-hydroxy) or the unusual 15R-prostaglandins. Their metabolic origin has remained the subject of mechanistic speculations for three decades. Here, we report the structu...
متن کاملBiochemical Warfare on the Reef: The Role of Glutathione Transferases in Consumer Tolerance of Dietary Prostaglandins
BACKGROUND Despite the profound variation among marine consumers in tolerance for allelochemically-rich foods, few studies have examined the biochemical adaptations underlying diet choice. Here we examine the role of glutathione S-transferases (GSTs) in the detoxification of dietary allelochemicals in the digestive gland of the predatory gastropod Cyphoma gibbosum, a generalist consumer of gorg...
متن کاملIs There a Trade-Off Between Wound-Healing and Chemical Defenses Among Caribbean Reef Sponges?1
SYNOPSIS. On Caribbean coral reefs, some sponge species produce chemical defenses, while others do not and are non-fatally grazed by predatory fishes. It has been hypothesized that the latter may compensate for fish grazing by growing faster or rapidly healing wounds. Rates of wound-healing were measured for chemically defended and undefended tubular and vase-shaped sponges on patch reefs in th...
متن کاملEvidence of a resource trade-off between growth and chemical defenses among Caribbean coral reef sponges
Like all organisms, sponges allocate resources to life functions such as growth and reproduction. Additionally, some sponges are defended by secondary metabolites that deter potential predators. Assuming resources are limiting, species that produce defensive metabolites should allocate fewer resources to growth and reproduction. To test the hypothesis that there is a trade-off between chemical ...
متن کاملEssential Oils of a Soft Coral (Sinularia sp) from Chabahar Bay of Iran
The essential oil extracted from the soft coral of Sinularia sp. have been extracted by soxhlet and analyzed by gas chromatography coupled to mass spectrometry (GC–MS). The principal compounds were found to be δ-Cadinene (12.4%), α-terpinene (10.7%) and α-Muurolene (8.3%). It is worth mentioning the presence of sesquiterpenes and diterpenes as main compounds of the essential oil. This is the fi...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید
ثبت ناماگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید
ورودعنوان ژورنال:
- Zeitschrift fur Naturforschung. C, Journal of biosciences
دوره 55 5-6 شماره
صفحات -
تاریخ انتشار 2000